AskCalc
Home › Surgery & Perioperative › Allowable blood loss

Maximum Allowable Blood Loss (ABL) Without Transfusion

Maximum allowable blood loss = estimated blood volume × (initial Hct − target Hct) ÷ average Hct, with blood volume 95 mL/kg (premature neonate), 85 (term neonate), 80 (infant), 75 (adult man) or 65 (adult woman). It estimates how much blood can be lost, with volume replaced, before reaching the transfusion threshold.

  • Weight (kg or lb)
  • Patient type (blood volume): Premature neonate (95 mL/kg); Term neonate (85 mL/kg); Infant (80 mL/kg); Adult man (75 mL/kg); Adult woman (65 mL/kg)
  • Initial hematocrit (%)
  • Target (lowest acceptable) hematocrit (%)
  • Blood volume override (mL/kg)
—

Formula

ABL = EBV × (Hi − Hf) ÷ Hav, where Hav = (Hi + Hf)/2. EBV = weight × blood volume per kg: premature neonate 95, term neonate 85, infant 80, adult man 75, adult woman 65 mL/kg. Hemoglobin can be substituted for hematocrit.

Clinical pearls

  • Assumes blood loss is replaced with crystalloid/colloid to keep normovolemia; it is a planning estimate, not a transfusion trigger.
  • Blood-volume values are conventional anesthesia reference values (premature 95, term neonate 85, infant 80, man 75, woman 65 mL/kg); use the override for children or obese patients if your reference differs (obese adults have less blood volume per kg).
  • Choose the target hematocrit by clinical context (e.g. coronary disease, ongoing bleeding) rather than a fixed number.

Examples

FAQ

How do you calculate maximum allowable blood loss?

Multiply estimated blood volume (weight × mL/kg) by the drop in hematocrit you can accept, divided by the average of the starting and target hematocrit.

What is the estimated blood volume of an adult?

About 75 mL/kg for men and 65 mL/kg for women; neonates and infants have more per kilogram (80–95 mL/kg).

Evidence

  1. Gross JB. Estimating allowable blood loss: corrected for dilution. Anesthesiology 1983;58:277–80.

Surgery & Perioperative · Reviewed 2026-10-14 · Methodology