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Caprini Risk Assessment Model for VTE (2005)

The 2005 Caprini risk assessment model sums weighted VTE risk factors (1, 2, 3 or 5 points each) in surgical patients. Scores 0–1 are low risk, 2 moderate, 3–4 high and ≥5 highest risk; pharmacologic prophylaxis is generally indicated from 3 points (ACCP 2012 "moderate") unless bleeding risk is high.

  • Age (years)
  • Minor surgery planned (yes/no, +1)
  • History of prior major surgery (< 1 month) (yes/no, +1)
  • Varicose veins (yes/no, +1)
  • History of inflammatory bowel disease (yes/no, +1)
  • Swollen legs (current) (yes/no, +1)
  • Obesity (BMI > 25) (yes/no, +1)
  • Acute myocardial infarction (yes/no, +1)
  • Congestive heart failure (< 1 month) (yes/no, +1)
  • Sepsis (< 1 month) (yes/no, +1)
  • Serious lung disease incl. pneumonia (< 1 month) (yes/no, +1)
  • Abnormal pulmonary function (COPD) (yes/no, +1)
  • Medical patient currently at bed rest (yes/no, +1)
  • Other risk factor (clinician judged) (yes/no, +1)
  • Women: oral contraceptives or hormone replacement therapy (yes/no, +1)
  • Women: pregnancy or postpartum (< 1 month) (yes/no, +1)
  • Women: unexplained stillbirth, ≥3 spontaneous abortions, or premature birth with toxemia / growth-restricted infant (yes/no, +1)
  • Arthroscopic surgery (yes/no, +2)
  • Malignancy (present or previous) (yes/no, +2)
  • Major surgery (> 45 minutes) (yes/no, +2)
  • Laparoscopic surgery (> 45 minutes) (yes/no, +2)
  • Patient confined to bed (> 72 hours) (yes/no, +2)
  • Immobilizing plaster cast (< 1 month) (yes/no, +2)
  • Central venous access (yes/no, +2)
  • History of DVT/PE (yes/no, +3)
  • Family history of thrombosis (yes/no, +3)
  • Positive factor V Leiden (yes/no, +3)
  • Positive prothrombin 20210A (yes/no, +3)
  • Elevated serum homocysteine (yes/no, +3)
  • Positive lupus anticoagulant (yes/no, +3)
  • Elevated anticardiolipin antibodies (yes/no, +3)
  • Heparin-induced thrombocytopenia (HIT) (yes/no, +3)
  • Other congenital or acquired thrombophilia (yes/no, +3)
  • Elective major lower-extremity arthroplasty (yes/no, +5)
  • Hip, pelvis or leg fracture (< 1 month) (yes/no, +5)
  • Stroke (< 1 month) (yes/no, +5)
  • Multiple trauma (< 1 month) (yes/no, +5)
  • Acute spinal cord injury with paralysis (< 1 month) (yes/no, +5)
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Interpretation

ResultMeaning
0–1Low risk
2Moderate risk
3–4High risk
≥ 5Highest risk

Formula

Age 41–60 = 1, 61–74 = 2, ≥75 = 3. 1 point: minor surgery, major surgery <1 mo, varicose veins, IBD, swollen legs, BMI >25, acute MI, CHF <1 mo, sepsis <1 mo, serious lung disease <1 mo, COPD, medical bed rest, other; women: OCP/HRT, pregnancy/postpartum, adverse obstetric history. 2 points: arthroscopic, malignancy, major surgery >45 min, laparoscopic >45 min, bed >72 h, cast <1 mo, central venous access. 3 points: prior DVT/PE, family history, factor V Leiden, prothrombin 20210A, homocysteine, lupus anticoagulant, anticardiolipin, HIT, other thrombophilia. 5 points: elective lower-extremity arthroplasty, hip/pelvis/leg fracture, stroke, multiple trauma, acute spinal cord injury (all <1 month).

Clinical pearls

  • Every applicable item is counted; unchecked items are treated as absent, as on the original checklist.
  • ACCP 2012 maps Caprini 0 = very low, 1–2 = low, 3–4 = moderate, ≥5 = high risk in general/abdominal-pelvic surgery.
  • Always weigh bleeding risk; use mechanical prophylaxis when bleeding risk is high.

Examples

FAQ

What Caprini score needs DVT prophylaxis?

At 3–4 points (moderate per ACCP) LMWH, low-dose heparin or IPC is suggested; at ≥5 pharmacologic prophylaxis is recommended, often extended to 4 weeks after cancer surgery.

Which version of the Caprini score is this?

The 2005 version published in Disease-a-Month, which most validation studies (e.g. Bahl 2010) used.

Evidence

  1. Caprini JA. Thrombosis risk assessment as a guide to quality patient care. Dis Mon 2005;51:70–8.
  2. Gould MK et al. Prevention of VTE in nonorthopedic surgical patients: ACCP 9th ed. Chest 2012;141(2 Suppl):e227S–e277S.

Surgery & Perioperative · Reviewed 2026-10-14 · Methodology