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Partial Mayo Score (Ulcerative Colitis)

The partial (non-invasive) Mayo score rates ulcerative colitis activity from stool frequency, rectal bleeding and physician global assessment (0–9) without endoscopy. Commonly: 0–1 remission, 2–4 mild, 5–6 moderate, 7–9 severe; a fall of ≥3 points best matched patient-reported improvement.

  • Stool frequency: Normal for patient (0); 1–2 stools/day more than normal (1); 3–4 stools/day more than normal (2); ≥5 stools/day more than normal (3)
  • Rectal bleeding: No blood seen (0); Streaks of blood with stool less than half the time (1); Obvious blood with stool most of the time (2); Blood alone passed (3)
  • Physician global assessment: Normal (0); Mild disease (1); Moderate disease (2); Severe disease (3)
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Interpretation

ResultMeaning
0–1Remission
2–4Mild
5–6Moderate
7–9Severe
Fall ≥3Clinical response (Lewis 2008 cut-point 2.5)

Formula

Partial Mayo = stool frequency (0–3) + rectal bleeding (0–3) + physician global assessment (0–3). The full Mayo score adds the endoscopic subscore (0–3).

Clinical pearls

  • Stool frequency is relative to the patient's own normal, not an absolute count.
  • Trials often define remission as partial Mayo ≤2 with no subscore >1; this is shown separately.
  • For hospitalized severe colitis use Truelove-Witts criteria.

Examples

FAQ

What is the difference between full and partial Mayo?

The partial Mayo omits the endoscopic subscore, so it ranges 0–9 instead of 0–12 and can be done at the bedside.

What partial Mayo score is remission?

Commonly 0–1; many trials use ≤2 with no individual subscore above 1.

Evidence

  1. Schroeder KW et al. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. N Engl J Med 1987;317:1625–9.
  2. Lewis JD et al. Use of the noninvasive components of the Mayo score to assess clinical response in ulcerative colitis. Inflamm Bowel Dis 2008;14:1660–6.

Hepatology & GI · Reviewed 2026-10-14 · Methodology