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ABIC Score (Alcoholic Hepatitis)

ABIC = 0.1 × age + 0.08 × bilirubin (mg/dL) + 0.3 × creatinine (mg/dL) + 0.8 × INR. It stratifies 90-day survival in alcohol-associated hepatitis: <6.71 low risk (~100%), 6.71–8.99 intermediate (~70%), ≥9.0 high risk (~25%).

Age (years)
Total bilirubin (mg/dL or µmol/L)
Serum creatinine (mg/dL or µmol/L)
INR

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Interpretation

Result	Meaning
< 6.71	Low risk (90-day survival ~100%)
6.71–8.99	Intermediate (~70%)
≥ 9.0	High risk (~25%)

Formula

ABIC = (age × 0.1) + (bilirubin mg/dL × 0.08) + (creatinine mg/dL × 0.3) + (INR × 0.8)

Clinical pearls

Derived in biopsy-proven alcoholic hepatitis (Barcelona); survival figures are from that cohort.
Bilirubin and creatinine must be in mg/dL; SI values are converted automatically when the unit is given.

Examples

abic 50 yo bili 10 cr 1.2 inr 1.8 ABIC score: age 60, bilirubin 400 umol/L, creatinine 180 umol/L, INR 2.5 abic age 40 bili 3 creat 0.7 inr 1.2

FAQ

What are the ABIC cut-offs?

6.71 and 9.0 separate low, intermediate and high risk of death at 90 days.

Evidence

Dominguez M et al. A new scoring system for prognostic stratification of patients with alcoholic hepatitis. Am J Gastroenterol 2008;103:2747–56.

Hepatology & GI · Reviewed 2026-10-14 · Methodology