Formula
Men: TBW = 2.447 − 0.09516 × age + 0.1074 × height (cm) + 0.3362 × weight (kg). Women: TBW = −2.097 + 0.1069 × height + 0.2466 × weight.
Clinical pearls
- Derived in healthy adults by isotope dilution; overestimates TBW in obesity less than weight-fraction rules, but is not validated in oedematous or critically ill patients.
- For quick bedside sodium and free-water calculations, a weight fraction (0.6 men, 0.5 women; less in elderly) is usually used instead.
Examples
FAQ
Why does the Watson formula ignore age in women?
In Watson's regression age did not add meaningful prediction for women, so the female equation uses only height and weight.
What is TBW used for?
Dialysis adequacy (Kt/V), drug and alcohol distribution volume, and sodium/free-water deficit calculations.