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CHA₂DS₂-VA Score (2024 ESC, sex-neutral)

CHA₂DS₂-VA is the 2024 ESC atrial fibrillation stroke-risk score: CHA₂DS₂-VASc without the female-sex point (0–8). Oral anticoagulation is recommended at ≥2 and should be considered at 1, with the same thresholds for men and women.

  • Age (years)
  • Congestive heart failure (yes/no, +1)
  • Hypertension (yes/no, +1)
  • Diabetes mellitus (yes/no, +1)
  • Prior stroke, TIA or arterial thromboembolism (yes/no, +2)
  • Vascular disease (prior MI, PAD, aortic plaque) (yes/no, +1)
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Interpretation

ResultMeaning
0Low risk: no OAC on the basis of the score
1OAC should be considered (Class IIa)
≥ 2OAC recommended (Class I)

Formula

C: CHF 1 · H: hypertension 1 · A₂: age ≥75 2 · D: diabetes 1 · S₂: prior stroke/TIA/arterial thromboembolism 2 · V: vascular disease 1 · A: age 65–74 1. (No sex category.)

Clinical pearls

  • Female sex was dropped because it acts as an age-dependent risk modifier rather than an independent risk factor; thresholds are now identical for men and women.
  • Not applicable to AF with a mechanical valve or moderate–severe mitral stenosis (anticoagulate regardless); hypertrophic cardiomyopathy and cardiac amyloidosis also warrant OAC irrespective of score.
  • North American (2023 ACC/AHA) guidance still uses CHA₂DS₂-VASc; see that calculator for sex-specific thresholds.

Examples

FAQ

What is the difference between CHA₂DS₂-VA and CHA₂DS₂-VASc?

CHA₂DS₂-VA removes the female-sex point (the "Sc"), so scores run 0–8 and the same thresholds apply to everyone: OAC recommended at ≥2 and considered at 1.

Which guideline uses CHA₂DS₂-VA?

The 2024 ESC atrial fibrillation guideline, in the absence of a locally validated risk score.

Evidence

  1. Van Gelder IC et al. 2024 ESC Guidelines for the management of atrial fibrillation. Eur Heart J 2024;45:3314–414.
  2. Rienstra M et al. Spotlight on the 2024 ESC/EACTS AF guidelines: 10 novel key aspects. Europace 2024.

Cardiology · Reviewed 2026-10-14 · Methodology