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CHA₂DS₂-VASc Score for Atrial Fibrillation Stroke Risk

CHA₂DS₂-VASc estimates annual stroke risk in non-valvular atrial fibrillation (0–9 points). Oral anticoagulation is recommended at ≥2 in men and ≥3 in women, and considered at 1 (men) or 2 (women).

  • Age (years)
  • Sex: Male; Female
  • Congestive heart failure history (yes/no, +1)
  • Hypertension (yes/no, +1)
  • Prior stroke, TIA or thromboembolism (yes/no, +2)
  • Vascular disease (prior MI, PAD, aortic plaque) (yes/no, +1)
  • Diabetes mellitus (yes/no, +1)
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Interpretation

ResultMeaning
0 (men) / 1 (women)Low risk; no antithrombotic therapy
1 (men) / 2 (women)Consider OAC
≥ 2 (men) / ≥ 3 (women)OAC recommended

Formula

C: CHF 1 · H: hypertension 1 · A₂: age ≥75 2 · D: diabetes 1 · S₂: stroke/TIA/TE 2 · V: vascular disease 1 · A: age 65–74 1 · Sc: female 1

Clinical pearls

  • Female sex is a risk modifier, not a risk factor on its own: a woman scoring 1 for sex alone is low risk.
  • Not for valvular AF (moderate–severe mitral stenosis or mechanical valve): those patients need anticoagulation regardless.

Examples

FAQ

When should a patient with AF be anticoagulated?

Guidelines recommend oral anticoagulation at CHA₂DS₂-VASc ≥2 in men or ≥3 in women, and consider it at 1 in men or 2 in women.

What is the difference between CHADS₂ and CHA₂DS₂-VASc?

CHA₂DS₂-VASc adds vascular disease, age 65–74 and female sex, and better identifies truly low-risk patients.

Evidence

  1. Lip GYH et al. Refining clinical risk stratification for predicting stroke and thromboembolism in AF. Chest 2010;137:263–72.
  2. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation.

Cardiology · Reviewed 2026-10-14 · Methodology