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ORBIT Bleeding Risk Score for Atrial Fibrillation

The ORBIT score (0–7) predicts major bleeding in AF patients on anticoagulation: 0–2 low (2.4 bleeds/100 patient-years), 3 medium (4.7), 4–7 high (8.1). Items: older age, reduced hemoglobin/anemia, bleeding history, insufficient kidney function, antiplatelet use.

  • Age (years)
  • Reduced Hb (< 13 g/dL men, < 12 women), Hct (< 40% men, < 36% women) or history of anemia (yes/no, +2)
  • Bleeding history (GI, intracranial or hemorrhagic stroke) (yes/no, +2)
  • Insufficient kidney function (eGFR < 60) (yes/no, +1)
  • Treatment with antiplatelet (yes/no, +1)
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Interpretation

ResultMeaning
0–2Low (2.4 bleeds/100 pt-yr)
3Medium (4.7)
4–7High (8.1)

Formula

O: older (≥ 75) 1 · R: reduced Hb/Hct or anemia history 2 · B: bleeding history 2 · I: insufficient kidney function (eGFR < 60) 1 · T: treatment with antiplatelet 1

Clinical pearls

  • ORBIT performed at least as well as HAS-BLED for predicting major bleeding and uses routinely available data.
  • Like HAS-BLED, a high score should prompt attention to modifiable factors rather than withholding anticoagulation.

Examples

FAQ

What does ORBIT stand for?

Older age (≥75), Reduced hemoglobin/hematocrit or anemia, Bleeding history, Insufficient kidney function (eGFR <60), and Treatment with antiplatelets.

ORBIT or HAS-BLED?

Both are acceptable; ORBIT is simpler to complete from labs, while HAS-BLED highlights more modifiable risk factors.

Evidence

  1. O'Brien EC et al. The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation. Eur Heart J 2015;36:3258–64.

Cardiology · Reviewed 2026-10-14 · Methodology