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eGFR (CKD-EPI 2021, race-free)

Estimates glomerular filtration rate from serum creatinine, age and sex using the race-free 2021 CKD-EPI creatinine equation, the current recommended equation in North America. Normal is ≥90 mL/min/1.73 m².

Serum creatinine (mg/dL or µmol/L)
Age (years)
Sex: Male; Female

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Interpretation

Result	Meaning
≥ 90	G1
60–89	G2
45–59	G3a
30–44	G3b
15–29	G4
< 15	G5

Formula

eGFR = 142 × min(Scr/κ, 1)^α × max(Scr/κ, 1)^−1.200 × 0.9938^age × 1.012 [if female]; κ = 0.7 (F) / 0.9 (M); α = −0.241 (F) / −0.302 (M)

Clinical pearls

Not valid in acute kidney injury (creatinine not at steady state).
For drug dosing, many labels still use Cockcroft-Gault creatinine clearance.

Examples

egfr creatinine 1.4 mg/dL 67 year old male gfr for 55F with creat 98 umol/L what is the kidney function of a 70 yo woman, cr 1.1

FAQ

Why was race removed from eGFR?

The 2021 CKD-EPI refit dropped the race coefficient after an NKF-ASN task force recommended race-free equations.

Evidence

Inker LA et al. New creatinine- and cystatin C–based equations to estimate GFR without race. N Engl J Med 2021;385:1737–49.

Nephrology & Electrolytes · Reviewed 2026-10-14 · Methodology